Pharmaceutics is the discipline of pharmacy that deals with all facets of the process or turning a new chemical entity (NCE) into a medication able to be safely and effectively used by patients in the community. Pharmaceutics deals with the formulation of pure drug substance into a dosage form. Branches of pharmaceutics include the study of relationship between drug formulation, delivery, disposition and clinical response.
Pharmaceutical Chemistry Lab
The laboratory of pharmaceutical chemistry is one of the central important branch of the institute. It is equipped with state of the art facilities to undertake academics in Bachelor of pharmacy course. In this lab, students learn about synthesis of pharmaceutical compounds, their re-crystallization (purification) identification and analysis. The laboratory is equipped with modern instrument like HPLC, U.V. spectrophotometer and polarimeter etc.
A separate laboratory is provided for this department. The main objective of this laboratory is to provide the deep knowledge of body parts and therapeutic effects of drug on various tissues and organs of body. Several minor experiments are conducted on human blood, determination of B.P Hemoglobin, Bleeding Time, E.S.R., D.L.C and T.L.C., detection of blood groups which provide the knowledge about health education and first aid in emergency.
Plant materials are used both in developed and developing countries as home remedies, over the counter drug products. Since ancient times plants have been the source of natural products and in today’s scenario several of them are model drugs for synthetic products. This lab is meant for extraction, isolation, purification, and identification of active chemical constituents from medicinal plants. The lab is equipped with modern equipments and instruments like Soxhlet extractors, compound microscopes, rotary evaporator, IR moisture balance, laminar air flow bench etc. The lab also has a good collection of crude drugs and their herbariums. At the end of the lab course, students are able to interpret the morphological and anatomical descriptions of the crude drugs and sound in terms of screening of plants for drug discovery.
Pharmaceutical Analysis Lab
Pharmaceutical Analysis is one of the most important specialized branches of Pharmaceutical Sciences concerned with the Quality Control of Pharmaceutical Products. Pharmaceutical analysis provides information on the identity, purity, content and stability of starting materials, excipients and active pharmaceutical ingredients (APIs). A distinction is made between analysis of the pure active ingredients used to cure, alleviate, prevent or identify illnesses and diseases (active ingredient analysis) and analysis of medicinal preparations.
Microbiology deals with the study of micro-organisms and is one of the fastest growing areas of science. The organisms are so small that they must be viewed with a microscope. These organisms are primarily bacteria, yeasts, molds, and viruses. The air conditioned lab of institute is well equipped with laminar air flow, incubator, auto clave, hot air oven etc.
GLOBAL INSTITUTE OF PHARMACEUTICAL EDUCATION & RESEARCH
(Approved by AICTE & PCI, Affiliated to Uttarakhand Technical University, Dehradun)Jaspur Road, Kashipur, Udham Singh Nagar (Uttarakhand)
Pharmaceutics Lab- I
B.Pharm.- VII Sem. Subject- Biopharmaceutics Paper Code- PHR- PHR 702P
|S.No.||Name of Experiment|
|1||To plot the graph between plasma drug concentration and time to estimate various pharmacokinetic and pharmacodynamic parameters.|
|2.||To plot the graph between plasma drug concentration and time to find AUC by trapezoidal method.|
|3.||To calculate pharmacokinetic parameter using plasma concentration and time following I.V administration of a drug representing one compartment model|
|4.||To prepare calibration curve of paracetamol.|
|5.||To perform invitro dissolution study of marketed tablet formulation of paracetamol|
|6.||To study the protein drug binding profile of marketed tablet formulation of metformin hydrochloride.|
|7.||To perform bioequivalence study of two different marketed brand of paracetamol tablet|
|8.||To perform invitro release study of marketed brand of metformin hydrochloride extended release tablet and study the mechanism of drug release.|
|9.||To calculate percentage absorb against time data via Wagner nelson method in which drug absorbed by apparent first order kinetic and follows pharmacokinetic characteristics of one compartment model. The drug is eliminated with a half-life of 8 hours.|
|10.||To study the effect of surfactant on invitro release profile of marketed brand of paracetamol.|
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